Sleeve gastrectomy

Introduction

Sleeve gastrectomy, also known as vertical sleeve gastrectomy (VSG), is a surgical weight-loss procedure that involves the removal of a large portion of the stomach, resulting in a sleeve or tube-like structure. This procedure is primarily used to treat morbid obesity, a condition characterized by an excessive accumulation of body fat that poses significant health risks. Sleeve gastrectomy is one of the most commonly performed bariatric surgeries worldwide due to its effectiveness in achieving substantial weight loss and improving obesity-related comorbidities.

Surgical Procedure

Preoperative Considerations

Before undergoing sleeve gastrectomy, patients typically undergo a comprehensive evaluation to assess their suitability for the procedure. This evaluation includes a thorough medical history, physical examination, and various diagnostic tests. Patients are often required to adhere to a preoperative diet to reduce liver size and facilitate the surgery. Psychological assessment is also crucial to ensure that patients have realistic expectations and are prepared for the lifestyle changes required post-surgery.

Operative Technique

The sleeve gastrectomy is performed laparoscopically, which involves the use of small incisions and specialized instruments. The surgeon begins by creating several small incisions in the abdomen to insert a laparoscope and other surgical tools. The stomach is then mobilized, and approximately 75-80% of the stomach is removed along the greater curvature. This resection results in a tubular stomach with a capacity of about 100-150 milliliters. The remaining stomach is stapled and sealed to prevent leakage.

Postoperative Care

Postoperative care is critical to ensure a successful recovery and includes pain management, monitoring for complications, and nutritional support. Patients are typically encouraged to begin ambulating soon after surgery to reduce the risk of deep vein thrombosis. A gradual transition from a liquid diet to solid foods is implemented over several weeks. Long-term follow-up is essential to monitor weight loss, nutritional status, and the resolution of comorbidities.

Mechanism of Action

The primary mechanism by which sleeve gastrectomy induces weight loss is through restriction. By significantly reducing the size of the stomach, the procedure limits the amount of food that can be consumed at one time. Additionally, the removal of the gastric fundus, which produces the hunger hormone ghrelin, may contribute to reduced appetite and increased satiety. This dual mechanism helps patients achieve and maintain significant weight loss.

Outcomes and Efficacy

Weight Loss

Sleeve gastrectomy has been shown to result in substantial weight loss, with patients typically losing 50-70% of their excess body weight within the first two years post-surgery. The procedure's effectiveness is comparable to other bariatric surgeries, such as Roux-en-Y gastric bypass, although individual results may vary.

Improvement in Comorbidities

In addition to weight loss, sleeve gastrectomy has been associated with improvements in various obesity-related comorbidities. These include type 2 diabetes, hypertension, dyslipidemia, and obstructive sleep apnea. The resolution or improvement of these conditions contributes to a reduction in overall mortality and an enhancement in quality of life.

Risks and Complications

While sleeve gastrectomy is generally considered safe, it is not without risks. Potential complications include bleeding, infection, leakage from the staple line, and gastroesophageal reflux disease (GERD). Long-term nutritional deficiencies, such as vitamin B12, iron, and calcium, may occur due to reduced food intake and altered digestion. Regular monitoring and supplementation are necessary to prevent these deficiencies.

Comparison with Other Bariatric Procedures

Sleeve gastrectomy is often compared to other bariatric procedures, such as gastric bypass and adjustable gastric banding. Each procedure has its advantages and disadvantages, and the choice of surgery depends on various factors, including patient preference, medical history, and surgeon expertise. Sleeve gastrectomy is favored for its simplicity, lower risk of complications, and effectiveness in weight loss and comorbidity resolution.

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