Cost-Effectiveness Analysis
Introduction
Cost-effectiveness analysis (CEA) is a form of economic analysis that compares the relative costs and outcomes (effects) of different courses of action. It is distinct from cost-benefit analysis, which assigns a monetary value to the measure of effect. CEA is often used in the field of health services, where it may be inappropriate to monetize health effect.


Methodology
CEA is typically expressed in the form of a ratio where the denominator is a gain in health from a measure (such as more individuals screened, life-years gained, deaths avoided, or cases detected) and the numerator is the cost associated with the health gain. The most commonly used outcome measure is Quality-Adjusted Life Years (QALY). QALY is a measure of the state of health of a person or group in which the benefits, in terms of length of life, are adjusted to reflect the quality of life. One QALY is equal to 1 year of life in perfect health. QALYs are calculated by estimating the years of life remaining for a patient following a particular treatment or intervention and weighting each year with a quality-of-life score (on a 0 to 1 scale). It is often measured in terms of the monetary cost of providing a medical service or intervention and the effect it has on a patient's life.
Application
CEA is used to evaluate the effectiveness of different interventions. It is a method that assists policy makers in the allocation of resources for disease prevention, health promotion, and treatment. This type of analysis is particularly important in healthcare, given the finite resources available for healthcare services. If one treatment is less effective and more costly than another, it is said to be dominated and the less costly, more effective treatment is preferred. If one treatment is both less effective and less costly than another treatment, a decision about the preferred treatment cannot be made without valuing the difference in effectiveness in monetary units.
Limitations
While CEA can provide important information about the average costs and effects of treatments, it does not provide information on the distribution of costs and effects in different individuals or groups. There are also challenges in measuring costs and effects. Costs are not always easy to measure, especially indirect costs such as the cost of patient time, and there is no consensus on the best way to measure health effects.
Conclusion
CEA is a valuable tool in healthcare and other fields for making decisions about resource allocation. It provides a systematic approach for evaluating the costs and effects of different interventions, which can help to inform policy decisions and improve health outcomes. However, it is not without limitations and should be used as one of many tools in the decision-making process.