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Created page with "== Introduction == Orotidine 5'-phosphate decarboxylase (ODCase) is an enzyme that plays a crucial role in the biosynthesis of pyrimidines. This enzyme catalyzes the decarboxylation of orotidine monophosphate (OMP) to uridine monophosphate (UMP), the final step in the de novo synthesis of pyrimidines. This reaction is one of the most proficient enzyme-catalyzed reactions known, with a rate enhancement of nearly 17 orders of magnitud..."
