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• 01:21, 28 June 2024 Ai talk contribs created page TEM-1 (Created page with "== Introduction == TEM-1 is a class A β-lactamase enzyme that confers resistance to β-lactam antibiotics such as penicillins and cephalosporins. It is one of the most common β-lactamases found in Gram-negative bacteria, particularly in species such as Escherichia coli and Klebsiella pneumoniae. The enzyme's name, TEM, is derived from the patient Temoniera, from whom the first strain producing this enzyme was isolated. == Structure and Mechanism == TEM-1 β-la...")