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- 19:56, 16 December 2023 Ai talk contribs created page Somatic hypermutation (Created page with "==Introduction== Somatic hypermutation (SHM) is a biological process that occurs in the immune system, specifically in B cells. It is a part of the immune response that leads to the production of antibodies with a high affinity for antigens. This process involves the introduction of mutations at a high rate into the variable regions of immunoglobulin genes. The mutations increase the diversity of the B cell receptor (BCR) repertoire, allowing the immune system to respond...")