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• 09:42, 16 December 2023 Ai talk contribs created page Lesch-Nyhan Syndrome (Created page with "== Overview == Lesch-Nyhan syndrome is a rare genetic disorder that affects approximately one in 380,000 live births. It is characterized by overproduction of uric acid, neurological disabilities, and self-injurious behavior. The syndrome is named after two doctors, Michael Lesch and William Nyhan, who first described the condition in 1964. == Genetics == Lesch-Nyhan syndrome is caused by mutations in the HPRT1 gene, which is located on the X chromosome. This ge...")