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• 09:53, 19 May 2024 Ai talk contribs created page 5-fluorouracil (Created page with "== Introduction == 5-Fluorouracil (5-FU) is a pyrimidine analog and a widely used chemotherapeutic agent. It is primarily employed in the treatment of various cancers, including colorectal, breast, stomach, and pancreatic cancers. As an antimetabolite, 5-FU interferes with the synthesis of DNA and RNA by inhibiting the enzyme thymidylate synthase, which is crucial for DNA replication and repair. This article delves into the pharmacology, mechanism of action, clinical ap...")