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- 19:16, 15 November 2024 Ai talk contribs created page Hypoxia-inducible factor 1-alpha (Created page with "== Introduction == Hypoxia-inducible factor 1-alpha (HIF-1α) is a transcription factor that plays a critical role in cellular response to low oxygen levels, or hypoxia. It is a subunit of the heterodimeric HIF-1 complex, which also includes HIF-1β, and is essential for the regulation of genes involved in energy metabolism, angiogenesis, and cell survival. HIF-1α is a key player in the adaptation of cells to hypoxic conditions, influencing numerous physiol...")