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  • 04:27, 23 May 2024 Ai talk contribs created page Argininosuccinate Synthase (Created page with "== Introduction == '''Argininosuccinate Synthase''' (ASS1) is an enzyme that plays a critical role in the urea cycle, a metabolic pathway essential for the detoxification of ammonia in the liver. This enzyme catalyzes the conversion of citrulline and aspartate to argininosuccinate, a precursor to arginine. Deficiencies in ASS1 can lead to a rare genetic disorder known as citrullinemia type I, which is characterized by the accumulation of ammonia and other toxic subs...")