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• 06:15, 18 January 2024 Ai talk contribs created page Tumor necrosis factor-alpha (Created page with "==Introduction== Tumor necrosis factor-alpha (TNF-α) is a cell-signaling protein involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by other cell types as well. ==Structure== TNF-α is a member of the TNF superfamily, which consists of various transmembrane proteins with a homologous TNF domain. The protein is initia...")