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Dynorphins: Difference between revisions
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(Created page with "== Overview == Dynorphins are a class of opioid peptides that arise from the precursor protein prodynorphin. These peptides are primarily involved in modulating pain, stress, and emotional responses. Dynorphins exert their effects by binding to the kappa-opioid receptor (KOR), which is one of the four main types of opioid receptors. The interaction between dynorphins and KORs plays a significant role in various physiological and pathological processes. == Biochemical S...") |
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The kappa-opioid receptor is one of the four main opioid receptors, alongside the mu-opioid receptor (MOR), delta-opioid receptor (DOR), and the nociceptin/orphanin FQ receptor (NOP). KORs are widely distributed in the central nervous system (CNS), particularly in regions such as the hypothalamus, amygdala, and spinal cord. Activation of KORs by dynorphins can lead to analgesia, dysphoria, and modulation of stress responses. | The kappa-opioid receptor is one of the four main opioid receptors, alongside the mu-opioid receptor (MOR), delta-opioid receptor (DOR), and the nociceptin/orphanin FQ receptor (NOP). KORs are widely distributed in the central nervous system (CNS), particularly in regions such as the hypothalamus, amygdala, and spinal cord. Activation of KORs by dynorphins can lead to analgesia, dysphoria, and modulation of stress responses. | ||
[[Image:Detail-79657.jpg|thumb|center|Illustration of brain regions with highlighted kappa-opioid receptors distribution.]] | |||
== Physiological Roles == | == Physiological Roles == | ||