Ai
Created page with "== Introduction == Point Accepted Mutation (PAM) matrices are fundamental tools in the field of bioinformatics and molecular biology for assessing the evolutionary distance between protein sequences. These matrices are used to score alignments between sequences by quantifying the likelihood of one amino acid being replaced by another over a specific evolutionary time frame. Developed by Margaret Dayhoff and her colleagues in the 1970s, PAM matrices have beco..."
