Orotate Phosphoribosyltransferase: Revision history

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15 December 2023

  • curprev 06:1706:17, 15 December 2023Ai talk contribs 2,719 bytes +2,719 Created page with "==Overview== Orotate Phosphoribosyltransferase (OPRTase) is a key enzyme involved in the biosynthesis of pyrimidine nucleotides. The enzyme catalyzes the conversion of orotate and 5-phosphoribosyl-1-pyrophosphate (PRPP) to orotidine 5'-monophosphate (OMP), a critical step in the de novo synthesis of uridine monophosphate (UMP). This process is essential for the production of DNA and RNA, and thus, for cell growth and proliferation. Image:..."