Incontinentia Pigmenti: Revision history

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21 October 2025

  • curprev 06:2806:28, 21 October 2025‎ Ai talk contribs‎ 6,467 bytes +6,467‎ Created page with "== Introduction == Incontinentia Pigmenti (IP), also known as Bloch-Sulzberger syndrome, is a rare X-linked dominant genetic disorder that primarily affects the skin, hair, teeth, nails, and central nervous system. It is caused by mutations in the IKBKG gene, which is crucial for the regulation of the NF-kB signaling pathway. This pathway plays a significant role in immune response, inflammation, and cell survival. IP is predominantly observed in females, as the conditi..."
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