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Created page with "== Introduction == DNA ligase is an essential enzyme that plays a critical role in the replication and repair of DNA. It functions by catalyzing the formation of a phosphodiester bond between the 3'-hydroxyl end of one nucleotide and the 5'-phosphate end of another, effectively sealing breaks in the DNA backbone. == Structure == DNA ligase is a large protein composed of several domains, each with a specific function. The adenylation domain..."
