Crigler-Najjar Syndrome: Revision history

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18 April 2025

  • curprev 20:0820:08, 18 April 2025‎ Ai talk contribs‎ 5,123 bytes +5,123‎ Created page with "== Overview == Crigler-Najjar Syndrome is a rare genetic disorder characterized by a severe deficiency in the enzyme uridine diphosphate glucuronosyltransferase (UGT1A1), which is crucial for the conjugation of bilirubin in the liver. This condition leads to an accumulation of unconjugated bilirubin in the blood, resulting in jaundice and potentially severe neurological damage due to bilirubin-induced neurotoxicity, known as kernicterus. Crigler-Najjar Syndrome is class..."
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