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• 14:35, 12 November 2024 Ai talk contribs created page Hereditary spastic paraplegia (Created page with "==Overview== Hereditary spastic paraplegia (HSP) is a group of inherited disorders characterized by progressive weakness and spasticity, primarily affecting the lower limbs. The condition is caused by degeneration of the corticospinal tracts, which are responsible for voluntary motor control. HSP is also known as familial spastic paraparesis or Strümpell-Lorrain syndrome. It is a clinically and genetically heterogeneous disorder, with over 80 different genetic types id...")