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- 07:21, 12 November 2024 Ai talk contribs created page Primary lateral sclerosis (Created page with "== Overview == Primary lateral sclerosis (PLS) is a rare neurological disorder characterized by progressive weakness and stiffness of the muscles. It is a type of motor neuron disease (MND) that affects the upper motor neurons, which are responsible for sending signals from the brain to the spinal cord. Unlike amyotrophic lateral sclerosis (ALS), which affects both upper and lower motor neurons, PLS primarily impacts the upper motor neurons, leading to a dis...")